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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
E2F8
All Species:
8.79
Human Site:
S357
Identified Species:
24.17
UniProt:
A0AVK6
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A0AVK6
NP_078956.2
867
94166
S357
I
S
P
N
T
S
G
S
S
P
V
I
H
F
T
Chimpanzee
Pan troglodytes
XP_508325
867
94169
S357
I
S
P
N
T
S
G
S
S
P
V
I
H
F
T
Rhesus Macaque
Macaca mulatta
XP_001095088
867
94195
S357
I
S
P
N
T
S
G
S
S
P
V
I
P
F
T
Dog
Lupus familis
XP_534087
864
93661
R357
I
S
P
S
P
S
G
R
G
P
V
L
P
L
P
Cat
Felis silvestris
Mouse
Mus musculus
Q58FA4
860
93258
G356
E
I
S
P
N
N
S
G
S
S
P
I
M
P
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506156
878
95490
P357
T
N
S
R
V
L
S
P
V
S
S
T
P
L
D
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001084876
724
79575
V222
P
L
V
K
H
P
E
V
G
F
V
E
L
P
G
Zebra Danio
Brachydanio rerio
XP_694311
917
100437
L369
D
I
P
S
P
K
D
L
E
I
S
T
T
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002321561
384
43173
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
96.6
89.6
N.A.
83
N.A.
N.A.
73.8
N.A.
48
39.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.3
98.1
94.2
N.A.
88.5
N.A.
N.A.
82.1
N.A.
59.9
55.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
46.6
N.A.
13.3
N.A.
N.A.
0
N.A.
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
60
N.A.
20
N.A.
N.A.
6.6
N.A.
6.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
20.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
30.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
0
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
0
0
0
0
0
12
0
0
0
0
0
0
0
12
% D
% Glu:
12
0
0
0
0
0
12
0
12
0
0
12
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
12
0
0
0
34
0
% F
% Gly:
0
0
0
0
0
0
45
12
23
0
0
0
0
0
12
% G
% His:
0
0
0
0
12
0
0
0
0
0
0
0
23
0
0
% H
% Ile:
45
23
0
0
0
0
0
0
0
12
0
45
0
0
0
% I
% Lys:
0
0
0
12
0
12
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
12
0
0
0
12
0
12
0
0
0
12
12
23
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% M
% Asn:
0
12
0
34
12
12
0
0
0
0
0
0
0
0
0
% N
% Pro:
12
0
56
12
23
12
0
12
0
45
12
0
34
23
12
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
12
0
0
0
12
0
0
0
0
0
0
0
% R
% Ser:
0
45
23
23
0
45
23
34
45
23
23
0
0
12
12
% S
% Thr:
12
0
0
0
34
0
0
0
0
0
0
23
12
0
34
% T
% Val:
0
0
12
0
12
0
0
12
12
0
56
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _